منابع مشابه
Primary HIV type 1 infection.
Emerging evidence suggests that early events in human immunodeficiency virus type 1 (HIV-1) infection may play a critical role in determining disease progression. Although there is limited evidence on which to base medical decisions, the diagnosis and treatment of acute HIV-1 infection may have virologic, immunologic, and clinical benefits. In addition, rapid diagnosis of infection may prevent ...
متن کاملEfficient Suppression of Minority Drug-Resistant HIV Type 1 (HIV-1) Variants Present at Primary HIV-1 Infection
BACKGROUND: Selection of preexisting minority variants of drug-resistant human immunodeficiency virus type 1 (HIV-1) can lead to virological failure in patients who receive antiretroviral therapy (ART) with low genetic resistance barriers. We studied treatment response and dynamics of minority variants during the first weeks of ART containing a ritonavir-boosted protease inhibitor (PI) and 2 nu...
متن کاملDiagnosis of Primary HIV-1 Infection
Results: Primary infection was diagnosed in 54 patients (12.4%). The sensitivity and specificity of the p24 antigen assay were 88.7% (95% CI, 77.0% to 95.7%) and 100% (CI, 99.3% to 100%), respectively. For the HIV RNA assay, sensitivity was 100% and specificity was 97.4% (CI, 94.9% to 98.9%). Fever, myalgia, rash, night sweats, and arthralgia occurred more frequently in patients with primary in...
متن کاملACUTE PRIMARY INFECTION WITH A HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) GROUP O: A PUZZLING DIAGNOSIS. Short title: HIV-1 group O primary infection
1 CHU Clermont-Ferrand, Laboratoire de Virologie, Hôpital Gabriel Montpied, F-63003 Clermont-Ferrand, France 3 CHU Clermont-Ferrand, Service de Maladies Infectieuses et Tropicales, Hôpital Gabriel Montpied, F-63003 Clermont-Ferrand, France 2 Centre Hospitalier Montluçon, Service de Dermatologie, F-03100 Montluçon, France 4 Centre Hospitalier Montluçon, Laboratoire, F-03100 Montluçon, France 5 L...
متن کاملCharacterization of human immunodeficiency virus type 1 (HIV-1) diversity and tropism in 145 patients with primary HIV-1 infection.
BACKGROUND In the context of sexual transmission of human immunodeficiency virus type 1 (HIV-1), current findings suggest that the mucosal barrier is the major site of viral selection, transforming the complex inoculum to a small, homogeneous founder virus population. We analyzed HIV-1 transmission in relation to viral and host characteristics within the Zurich primary HIV-1 infection study. ...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2004
ISSN: 1058-4838,1537-6591
DOI: 10.1086/420745